abstract：:The integrated assessment of nutritional status and presence of sarcopenia would help improve clinical outcomes of in-hospital aged patients. We compared three common nutritional screening tools with the new Global Leadership Initiative on Malnutrition (GLIM) diagnostic criteria among hospitalized older patients. To t...

journal_title：Journal of clinical medicine

authors： Bellanti F,Lo Buglio A,Quiete S,Pellegrino G,Dobrakowski M,Kasperczyk A,Kasperczyk S,Vendemiale G

更新日期：2020-06-17 00:00:00

abstract：:Endometrial cancer (EC) is the sixth most common cancer in women worldwide and its mortality is directly associated with the presence of poor prognostic factors driving tumor recurrence. Stratification systems are based on few molecular, and mostly clinical and pathological parameters, but these systems remain inaccur...

journal_title：Journal of clinical medicine

authors： Coll-de la Rubia E,Martinez-Garcia E,Dittmar G,Gil-Moreno A,Cabrera S,Colas E

更新日期：2020-06-17 00:00:00

abstract：:Endoscopic resection is recommended for gastric neoplasms confined to mucosa or superficial submucosa. The determination of invasion depth is based on gross morphology assessed in endoscopic images, or on endoscopic ultrasound. These methods have limited accuracy and pose an inter-observer variability. Several studies...

journal_title：Journal of clinical medicine

authors： Cho BJ,Bang CS,Lee JJ,Seo CW,Kim JH

更新日期：2020-06-15 00:00:00

abstract：:The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed YWHAZ (encoding 14-3-3ζ) as a candidate gene for autism spectrum disorder (ASD) through a whole-exome sequencing study, which identified a frameshift variant within the gene (...

journal_title：Journal of clinical medicine

authors： Torrico B,Antón-Galindo E,Fernàndez-Castillo N,Rojo-Francàs E,Ghorbani S,Pineda-Cirera L,Hervás A,Rueda I,Moreno E,Fullerton JM,Casadó V,Buitelaar JK,Rommelse N,Franke B,Reif A,Chiocchetti AG,Freitag C,Kleppe R,Haavik

更新日期：2020-06-13 00:00:00

abstract：:α-Klotho is a known anti-aging protein that exerts diverse physiological effects, including phosphate homeostasis. Klotho expression occurs predominantly in the kidney and is significantly decreased in patients with chronic kidney disease. However, changes in serum klotho levels and impacts of klotho on outcomes among...

journal_title：Journal of clinical medicine

authors： Thongprayoon C,Neyra JA,Hansrivijit P,Medaura J,Leeaphorn N,Davis PW,Kaewput W,Bathini T,Salim SA,Chewcharat A,Aeddula NR,Vallabhajosyula S,Mao MA,Cheungpasitporn W

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Invasive fungal disease (IFD) is common in solid organ transplant (SOT) recipients and contributes to high morbidity and mortality. Although kidney transplantation (KT) is a commonly performed SOT, data on the risk factors for IFD-related mortality are limited. METHODS:A 1:2 retrospective case-control study...

journal_title：Journal of clinical medicine

authors： Seok H,Huh K,Cho SY,Kang CI,Chung DR,Huh WS,Park JB,Peck KR

更新日期：2020-06-11 00:00:00

abstract：:Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical routine practice is imperative. This study aims to provide pilot data regarding PRP application for ovarian rejuvenation. Four pilot ...

journal_title：Journal of clinical medicine

authors： Sfakianoudis K,Simopoulou M,Grigoriadis S,Pantou A,Tsioulou P,Maziotis E,Rapani A,Giannelou P,Nitsos N,Kokkali G,Koutsilieris M,Pantos K

更新日期：2020-06-10 00:00:00

abstract：:Background: Patients with pulmonary embolism (PE) may suffer from long-term consequences, including decreased functional capacity. Data on pulmonary rehabilitation (PR) in patients with PE are scarce, and no data on outpatient PR are available so far. Methods: We analyzed data of 22 PE patients who attended outpatient...

journal_title：Journal of clinical medicine

authors： Nopp S,Klok FA,Moik F,Petrovic M,Derka I,Ay C,Zwick RH

更新日期：2020-06-10 00:00:00

abstract：:Contemporary minimally invasive surgical (MIS) treatment options of patients with male Lower Urinary Tract Symptoms (LUTS) in men with prostate glands >80 mL include Holmium Laser Enucleation Prostate (HoLEP), Thulium laser VapoEnucleation Prostate (ThuVEP), and Laparoscopic (LSP) or Robotic-Assisted Simple Prostatect...

journal_title：Journal of clinical medicine

authors： Kordan Y,Canda AE,Köseoğlu E,Balbay D,Laguna MP,de la Rosette J

更新日期：2020-06-09 00:00:00

abstract：:This study aims to evaluate clinical and ulcer characteristics as well the outcomes of patients with diabetic foot ulcers (DFUs). The study group was composed of DFUs patients managed by a limb salvage protocol according to guidance. Clinical and ulcers findings were described, and 1-year outcomes defined as limb salv...

journal_title：Journal of clinical medicine

authors： Meloni M,Izzo V,Giurato L,Lázaro-Martínez JL,Uccioli L

更新日期：2020-06-08 00:00:00

abstract：:The diagnosis of hereditary hemorrhagic telangiectasia (HHT) is based on the Curaçao criteria: epistaxis, telangiectases, arteriovenous malformations in internal organs, and family history. Genetically speaking, more than 90% of HHT patients show mutations in ENG or ACVRL1/ALK1 genes, both belonging to the TGF-β/BMP9 ...

journal_title：Journal of clinical medicine

authors： Albiñana V,Cuesta AM,Rojas-P I,Gallardo-Vara E,Recio-Poveda L,Bernabéu C,Botella LM

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Oral and enteral mucositis due to high-dose cytostatic treatment administered during autologous and allogeneic stem-cell transplantation increases mortality. Salivary secretory immunoglobulin A (sIgA) is a basic pillar of local immunity in the first line of defense. Altered salivary sialoglycoprotein carbohy...

journal_title：Journal of clinical medicine

authors： Gebri E,Kovács Z,Mészáros B,Tóth F,Simon Á,Jankovics H,Vonderviszt F,Kiss A,Guttman A,Hortobágyi T

更新日期：2020-06-05 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide concern. SARS-CoV-2 has spread to 210 countries worldwide and more than 6,500,000 confirmed cases and 384,643 deaths have been reported, while the number of...

journal_title：Journal of clinical medicine

authors： Baj J,Karakuła-Juchnowicz H,Teresiński G,Buszewicz G,Ciesielka M,Sitarz E,Forma A,Karakuła K,Flieger W,Portincasa P,Maciejewski R

更新日期：2020-06-05 00:00:00

abstract：:Adipokines are powerful agents involved in the development of obesity-dependent cancers. This prospective study aimed to investigate the association between pre-treatment body mass index (BMI) and serum YKL-40, leptin, and adiponectin concentrations as well as the plasma activity of tissue factor (TF) and the future p...

journal_title：Journal of clinical medicine

authors： Bielawski K,Rhone P,Bulsa M,Ruszkowska-Ciastek B

更新日期：2020-06-04 00:00:00

abstract：:Background: Due to the higher frequency of ischemic stroke in men compared to women, we aimed to determine if gender differences exist regarding periodontal status and several plasma biomarkers in patients with a recent large artery atherosclerosis ischemic stroke (IS). Material and methods: Patients with their first ...

journal_title：Journal of clinical medicine

authors： Stănescu I,Bulboacă AE,Micu IC,Bolboacă SD,Feștilă DG,Bulboacă AC,Bodizs G,Dogaru G,Boarescu PM,Popa-Wagner A,Roman A

更新日期：2020-06-04 00:00:00

abstract：:The aim of this study was to investigate whether early intermittent electroencephalography (EEG) could be used to predict neurological prognosis of patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR). This was a retrospective and observational study of adult patients who were evaluated by EEG sc...

journal_title：Journal of clinical medicine

authors： Kim YO,Ko RE,Chung CR,Yang JH,Park TK,Cho YH,Sung K,Suh GY,Ryu JA

更新日期：2020-06-04 00:00:00

abstract：:The outcome of coronavirus disease 2019 (COVID-19) is associated with organ damage; however, the information about the relationship between acute kidney injury (AKI) and COVID-19 is still rare. We evaluated the clinical features and prognosis of COVID-19 patients with AKI according to the AKI severity. Medical data of...

journal_title：Journal of clinical medicine

authors： Lim JH,Park SH,Jeon Y,Cho JH,Jung HY,Choi JY,Kim CD,Lee YH,Seo H,Lee J,Kwon KT,Kim SW,Chang HH,Kim YL

更新日期：2020-06-03 00:00:00

abstract：:Diagnoses based on oral fluid biomarkers have been introduced to overcome limitations of periodontal probe-based diagnoses. Diagnostic ability of certain biomarkers for periodontitis have been identified and widely studied, however, such studies targeting gingivitis is scarce. The aims of this study were to determine ...

journal_title：Journal of clinical medicine

authors： Hong I,Pae HC,Song YW,Cha JK,Lee JS,Paik JW,Choi SH

更新日期：2020-06-03 00:00:00

abstract：:Patients diagnosed with traumatic or non-traumatic spinal pain and idiopathic scoliosis frequently suffer from imbalance. The evaluation of the perception of verticality by means of visual tests emerges as a quick and easy tool for clinical management of the balance disorders. Several studies have assessed the visual ...

journal_title：Journal of clinical medicine

authors： Obrero-Gaitán E,Molina F,Del-Pino-Casado R,Ibáñez-Vera AJ,Rodríguez-Almagro D,Lomas-Vega R

更新日期：2020-06-03 00:00:00

abstract：:To date, MRI studies focused on brain sexual dimorphism have not explored the presence of specific neural patterns in gender dysphoria (GD) using gender discrimination tasks. Considering the central role of body image in GD, the present study aims to evaluate brain activation patterns with 3T-scanner functional MRI (f...

journal_title：Journal of clinical medicine

authors： Fisher AD,Ristori J,Castellini G,Cocchetti C,Cassioli E,Orsolini S,Sensi C,Romani A,Mazzoli F,Cipriani A,Ricca V,Vignozzi L,Viggiano MP,Mascalchi M,Maggi M,Gavazzi G

更新日期：2020-06-03 00:00:00

abstract：:Since an association between myocardial infarction (MI) and respiratory infections has been described for influenza viruses and other respiratory viral agents, understanding possible physiopathological links between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and acute coronary syndromes (ACS) is of t...

journal_title：Journal of clinical medicine

authors： Schiavone M,Gobbi C,Biondi-Zoccai G,D'Ascenzo F,Palazzuoli A,Gasperetti A,Mitacchione G,Viecca M,Galli M,Fedele F,Mancone M,Forleo GB

更新日期：2020-06-02 00:00:00

abstract：:Adjustment disorders (AjD) with depressive symptoms following an acquired brain injury (ABI) is a common phenomenon. Although brain injuries are increasing more and more, research on psychological therapies is comparably scarce. The present study compared, by means of a randomized controlled trial (RCT), a newly devel...

journal_title：Journal of clinical medicine

authors： Urech A,Krieger T,Frischknecht E,Stalder-Lüthy F,Grosse Holtforth M,Müri RM,Znoj H,Hofer H

更新日期：2020-06-02 00:00:00

abstract：:Acute kidney injury (AKI) is characterized by an acute decrease in renal function that can be multifactorial in its origin and is associated with complex pathophysiological mechanisms. In the short term, AKI is associated with an increased length of hospital stay, health care costs, and in-hospital mortality, and its ...

journal_title：Journal of clinical medicine

authors： Gameiro J,Fonseca JA,Outerelo C,Lopes JA

更新日期：2020-06-02 00:00:00

abstract：:Continuous positive airway pressure (CPAP) is the most efficient treatment of obstructive sleep apnea (OSA). Little is known about the impact of spousal relationship profiles on CPAP adherence. We aimed to identify clusters of couples of OSA patients, and their association with CPAP adherence 120 days after CPAP initi...

journal_title：Journal of clinical medicine

authors： Mendelson M,Gentina T,Gentina E,Tamisier R,Pépin JL,Bailly S

更新日期：2020-06-01 00:00:00

abstract：:Pulmonary hypertension (PH) in patients with heart failure (HF) contributes to a poorer prognosis. However, in those with dilated cardiomyopathy (DCM), the true prevalence and role of PH is unclear. Therefore, this study aimed to analyze the profile of DCM patients at various levels of PH risk, determined via echocard...

journal_title：Journal of clinical medicine

authors： Dziewięcka E,Wiśniowska-Śmiałek S,Karabinowska A,Holcman K,Gliniak M,Winiarczyk M,Karapetyan A,Kaciczak M,Podolec P,Kostkiewicz M,Hlawaty M,Leśniak-Sobelga A,Rubiś P

更新日期：2020-06-01 00:00:00

abstract：:Thyroid hormones (THs) exert pleiotropic effects in different mammalian organs, including gonads. Genetic and non-genetic factors, such as ageing and environmental stressors (e.g., low-iodine intake, exposure to endocrine disruptors, etc.), can alter T4/T3 synthesis by the thyroid. In any case, peripheral T3, controll...

journal_title：Journal of clinical medicine

authors： Colella M,Cuomo D,Giacco A,Mallardo M,De Felice M,Ambrosino C

更新日期：2020-06-01 00:00:00

abstract：:* Correspondence: kasiajanda@op [...]. ...

journal_title：Journal of clinical medicine

authors： Woziwodzka K,Vesole DH,Małyszko J,Batko K,Jurczyszyn A,Koc-Żórawska E,Krzanowski M,Małyszko J,Żórawski M,Waszczuk-Gajda A,Kuźniewski M,Krzanowska K

更新日期：2020-05-31 00:00:00

abstract：:About one-fifth of couples has fertility problems in Western countries. Male factors are present in about half of them, either alone or in combination with female causes. Therefore, both partners should be evaluated simultaneously. The fertility status and/or specific conditions of each partner influence the clinical ...

journal_title：Journal of clinical medicine

authors： Ferlin A,Foresta C

更新日期：2020-05-30 00:00:00

abstract：:(1) Objective: To compare the accuracy of different indexes of adiposity and/or body composition in identifying metabolic syndrome (MetS) in adult patients suffering from Prader‒Willi syndrome (PWS). (2) Study Design: One hundred and twenty PWS patients (69 females and 51 males), aged 29.1 ± 9.4 years, body mass index...

journal_title：Journal of clinical medicine

authors： Radetti G,Fanolla A,Lupi F,Sartorio A,Grugni G

更新日期：2020-05-30 00:00:00

abstract：OBJECTIVES:Central neurological manifestations of rheumatoid arthritis (RA) like rheumatoid meningitis (RM) are rare, little known and have a high rate of morbi-mortality. METHODS:We described six cases of RM that were directly related to RA activity after exhaustive assessment. RESULTS:They were mainly women, aged o...

journal_title：Journal of clinical medicine

authors： Trabelsi M,Romand X,Gilson M,Vaillant M,Guerne PA,Hayem G,Bertolini E,Baillet A,Gaudin P

更新日期：2020-05-27 00:00:00

abstract：:The superiority of distinct anesthesia methods for geriatric hip fracture surgery remains unclear. We evaluated high mobility group box-1 (HMGB1) and interleukin-6 (IL-6) with three different anesthesia methods in elderly patients undergoing hip fracture surgery. Routine blood test findings, postoperative morbidity, a...

journal_title：Journal of clinical medicine

authors： Shin S,Kim SH,Park KK,Kim SJ,Bae JC,Choi YS

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:When a rescuer walks alongside a stretcher and compresses the patient's chest, the rescuer produces low-quality chest compressions. We hypothesized that a stretcher equipped with wing boards allows for better chest compressions than the conventional method. METHODS:In this prospective, randomized, crossover...

journal_title：Journal of clinical medicine

authors： Nakashima Y,Saitoh T,Yasui H,Ueno M,Hotta K,Ogawa T,Takahashi Y,Maekawa Y,Yoshino A

更新日期：2020-05-23 00:00:00

abstract：:The UBE3A gene codes for a protein with two known functions, a ubiquitin E3-ligase which catalyzes ubiquitin binding to substrate proteins and a steroid hormone receptor coactivator. UBE3A is most famous for its critical role in neuronal functioning. Lack of UBE3A protein expression leads to Angelman syndrome (AS), wh...

journal_title：Journal of clinical medicine

authors： Simchi L,Panov J,Morsy O,Feuermann Y,Kaphzan H

更新日期：2020-05-22 00:00:00

abstract：:The evolution of implant dentistry since the discovery of the osseointegration concept has been remarkable [...]. ...

journal_title：Journal of clinical medicine

authors： de Araújo Nobre M

更新日期：2020-05-22 00:00:00

abstract：BACKGROUND:In mildly to moderately malnourished adolescent patients with anorexia nervosa (AN), accelerated refeeding protocols using higher initial calory supply coupled with phosphate supplements were not associated with a higher incidence of refeeding syndrome (RS). It is unclear whether this is also a feasible appr...

journal_title：Journal of clinical medicine

authors： Koerner T,Haas V,Heese J,Karacic M,Ngo E,Correll CU,Voderholzer U,Cuntz U

更新日期：2020-05-19 00:00:00

abstract：:Despite extensive research and development of new treatments, acute myeloid leukemia (AML)-backbone therapy has remained essentially unchanged over the last decades and is frequently associated with poor outcomes. Eradicating the leukemic stem cells (LSCs) is the ultimate challenge in the treatment of AML. Emerging ev...

journal_title：Journal of clinical medicine

authors： Pievani A,Biondi M,Tomasoni C,Biondi A,Serafini M

更新日期：2020-05-18 00:00:00

abstract：:Hemorrhagic strokes account for half of all strokes seen in children, and the etiologies of these hemorrhagic strokes differ greatly from those seen in adult patients. This review gives an overview about incidence and etiologies as well as presentation of children with intracerebral hemorrhage and with differential di...

journal_title：Journal of clinical medicine

authors： Sporns PB,Psychogios MN,Fullerton HJ,Lee S,Naggara O,Boulouis G

更新日期：2020-05-18 00:00:00

abstract：:In recent years, the genetic architecture of dilated cardiomyopathy (DCM) has been more thoroughly elucidated. However, there is still insufficient knowledge on the modifiers and regulatory principles that lead to the failure of myocardial function. The current study investigates the association of epigenome-wide DNA ...

journal_title：Journal of clinical medicine

authors： Gi WT,Haas J,Sedaghat-Hamedani F,Kayvanpour E,Tappu R,Lehmann DH,Shirvani Samani O,Wisdom M,Keller A,Katus HA,Meder B

更新日期：2020-05-16 00:00:00

abstract：:The purpose of this study was to compare the thickness of all inner and outer macular layers between ocular hypertension (OHT) and early primary open-angle glaucoma (POAG) using spectral domain optical coherence tomography (SD-OCT) 8 × 8 posterior pole algorithm (8 × 8 PPA). Fifty-seven eyes of 57 OHT individuals and ...

journal_title：Journal of clinical medicine

authors： Garcia-Medina JJ,Del-Rio-Vellosillo M,Palazon-Cabanes A,Pinazo-Duran MD,Zanon-Moreno V,Villegas-Perez MP

更新日期：2020-05-16 00:00:00

abstract：:There is increasing data in favour of follicle-stimulating hormone (FSH) therapy in patients with oligo-asthenozoospermia and normal-range gonadotropins in order to increase sperm count and above all sperm motility. Some studies showed an improvement in DNA fragmentation and spontaneous pregnancy. Recently, biosimilar...

journal_title：Journal of clinical medicine

authors： De Rocco Ponce M,Foresta C,Rago R,Dal Lago A,Balercia G,Calogero AE,La Vignera S,Cosci I,Di Nisio A,Garolla A

更新日期：2020-05-14 00:00:00